Sun Tian
I am a bioinfomratics scientist at Carbon Logic Biotech(HK) Ltd. My work mainly focuses on target discovery/target validation/biomarker of immunotherapy and colorectal cancer. Publications and patents see
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Sun Tian, Wang Huajun, Jianhua Wu. (2012) Computational prediction of furin cleavage sites by a hybrid method and understanding mechanism underlying diseases. Scientific Reports. 2, 261.
- Supplementary material:
1. PiTou Furin cleavage site computational prediction tool download guide (excutable file on Windows platform): download
Sun Tian, Qingsheng Huang, Ying Fang, Jianhua Wu. (2011) FurinDB: a database of 20-residue furin cleavage site motifs, substrates and their associated drugs. International Journal of Molecular Sciences., 12, 1060-1065.
Sun Tian and Wu Jianhua. (2010) Comparative study of the binding pockets of mammalian proprotein convertases and its implications for the design of specific small molecule inhibitors. International Journal of Biological Sciences., 2010, 6, 89-95.
- Supplementary material:
Multiple sequence alignment of the binding pockets of mammalian proprotein convertases : download
Sun Tian. (2009) A 20 Residues Motif Delineates the Furin Cleavage Site and its Physical Properties May Influence Viral Fusion. Biochemistry Insights., 2, 9-20.
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Supplementary material:
List of all correlation coefficient R > 0.65 in region P14--P6' on the Furin cleavage site motif: download