Furin Cleavage Bioinformatics
- Analyze furin cleavage sites in protein sequences from different organisms: mammal, bactria and virus, and investigate biology of furin substrates
- Develop database and computational tools for furin cleavage
- Study molecular mechanism of furin cleavage associated human diseases, design drugs targeting proteolytic cleavage of furin and other proprotein convertases
Sun Tian*, Qingsheng Huang*, Ying Fang, Jianhua Wu. (2011)
FurinDB: a database of 20-residue furin cleavage site motifs, substrates and their associated drugs.
International Journal of Molecular Sciences., 12, 1060-1065. (*equal contribution)
Scientific and technical comments: Sun Tian